{"id":75653,"date":"2020-12-28T09:17:17","date_gmt":"2020-12-28T07:17:17","guid":{"rendered":"https:\/\/ovagenesis.eu\/low-ovarian-potential-how-do-we-deal-with-it\/"},"modified":"2025-11-17T12:41:25","modified_gmt":"2025-11-17T10:41:25","slug":"low-ovarian-potential-how-do-we-deal-with-it-2","status":"publish","type":"post","link":"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/","title":{"rendered":"Low ovarian potential: How do we deal with it?"},"content":{"rendered":"\n<p>Article from Dr. Garavelas Athanasios, Gynecologist Fertility Specialist.<\/p>\n\n\n\n<p>The development and maturation of multiple follicles is crucial for achieving IVF pregnancies. A significant percentage of women, however, who undergo ovarian stimulation as part of assisted reproduction do not adequately respond to standard ovarian stimulation protocols with a significantly reduced number of developing follicles. These women are defined as &#8220;poor responders&#8221; and usually show reduced oocyte counts, low fertilization rates, poor fetal quality and, consequently, low pregnancy rates.<\/p>\n\n\n\n<p>&#8211; Poor ovarian response occurs in 9-24% of women undergoing ovarian stimulation and requires a special therapeutic approach and treatment.<\/p>\n\n\n\n<p>&#8211; Until recently, there was virtually no understanding of the definition of &#8220;poor ovarian response&#8221;, resulting in significant difficulty in assessing the effectiveness of various methods of treating poor ovarian response based on relevant published studies. Recently, in an attempt to establish a universally accepted definition of &#8220;poor ovarian response&#8221;, it was suggested that: a woman be classified as a &#8220;poor responder&#8221; if at least two of the three criteria are present:<\/p>\n\n\n\n<p>a) advanced age of the woman (\u2265 40 years) or the presence of another risk factor for poor ovarian response;<\/p>\n\n\n\n<p>b) previous poor ovarian<\/p>\n\n\n\n<p>c) abnormal ovarian reserve (M\u03cbller pore inhibitory hormone (AMH) 0.5-1.1 ng \/ ml).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" data-src=\"https:\/\/garavelas.com\/wp-content\/uploads\/2020\/12\/texniti-gonimopoiisi.jpg\" alt=\"\" class=\"wp-image-2093 lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" \/><\/figure>\n\n\n\n<p>Two episodes of poor ovarian response after maximal ovarian stimulation are considered sufficient to characterise a patient as a &#8220;poor responder&#8221; in the absence of advanced age or abnormal ovarian reserve. Causes of poor ovarian response include a woman&#8217;s advanced age, previous ovarian surgery, pelvic adhesions, and increased body mass index. <\/p>\n\n\n\n<p>However, a poor ovarian response can also occur unexpectedly, reflecting premature ovarian aging.Dealing with poor responders remains a challenge in the field of assisted reproduction.The options given to a woman who has a reduced ovarian supply and is a poor respondent are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The natural IVF cycle, although it has its difficulties, has been an excellent tool in the hands of an experienced IVF specialist.Ovarian rejuvenation (PRP PLATELET RICH PLASMA) is a new experimental process that helps in the natural production of oocytes in the ovaries. <\/li><li>It is a worthwhile alternative to egg donation. In addition, it offers hope to women who are in advanced reproductive age and have a reduced number and usually of poor quality eggs.<\/li><li>Essentially, however, the choice with the highest pregnancy rates is egg donation. It is a simple medical technique but a complex process both emotionally and psychologically for the couple who will decide to make this choice. But the message I have to convey as a scientist and human being is simple and lies in the fact that in no case can the achievement of pregnancy be ruled out, whatever the image of ovarian function.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>The development and maturation of multiple follicles is crucial for achieving IVF pregnancies. A significant percentage of women, however, who undergo ovarian stimulation as part of assisted reproduction do not adequately respond to standard ovarian stimulation protocols with a significantly reduced number of developing follicles.<\/p>\n","protected":false},"author":1,"featured_media":75623,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-75653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.4 (Yoast SEO v26.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Low ovarian potential: How do we deal with it? - OVAGENESIS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Low ovarian potential: How do we deal with it?\" \/>\n<meta property=\"og:description\" content=\"The development and maturation of multiple follicles is crucial for achieving IVF pregnancies. A significant percentage of women, however, who undergo ovarian stimulation as part of assisted reproduction do not adequately respond to standard ovarian stimulation protocols with a significantly reduced number of developing follicles.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\" \/>\n<meta property=\"og:site_name\" content=\"OVAGENESIS\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Dr.Garavelas.IVF?locale=el_GR\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-28T07:17:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-17T10:41:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ovagenesis.dope.studio\/wp-content\/uploads\/2020\/11\/Healthy-woman.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"984\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ovagenesis\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\"},\"author\":{\"name\":\"ovagenesis\",\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/#\/schema\/person\/d030a1e371c9bf180496a7d14afada63\"},\"headline\":\"Low ovarian potential: How do we deal with it?\",\"datePublished\":\"2020-12-28T07:17:17+00:00\",\"dateModified\":\"2025-11-17T10:41:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\"},\"wordCount\":459,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/#organization\"},\"image\":{\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ovagenesis.dope.studio\/wp-content\/uploads\/2020\/11\/Healthy-woman.jpg\",\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\",\"url\":\"https:\/\/ovagenesis.dope.studio\/en\/low-ovarian-potential-how-do-we-deal-with-it-2\/\",\"name\":\"Low ovarian potential: How do we deal with it? 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